Biochemistry / Neurology & Clinical Neurophysiology / Pharmacology / Physiology

Brain Lipids in Synaptic Function and Neurological Disease : Clues to Innovative Therapeutic Strategies for Brain Disorders

Brain Lipids in Synaptic Function and Neurological Disease : Clues to Innovative Therapeutic Strategies for Brain Disorders

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Additional Information

ISBNPublisherWeight
9780128001110Elsevier|Health Sciences0.95 Kg

Description

Lipids are the most abundant organic compounds found in the brain, accounting for up to 50% of its...Read More

Description

Lipids are the most abundant organic compounds found in the brain, accounting for up to 50% of its dry weight. The brain lipidome includes several thousands of distinct biochemical structures whose expression may greatly vary according to age, gender, brain region, cell type, as well as subcellular localization. In synaptic membranes, brain lipids specifically interact with neurotransmitter receptors and control their activity. Moreover, brain lipids play a key role in the generation and neurotoxicity of amyloidogenic proteins involved in the pathophysiology of neurological diseases. The aim of this book is to provide for the first time a comprehensive overview of brain lipid structures, and to explain the roles of these lipids in synaptic function, and in neurodegenerative diseases, including Alzheimer’s, Creutzfeldt-Jakob’s and Parkinson’s. To conclude the book, the authors present new ideas that can drive innovative therapeutic strategies based on the knowledge of the role of lipids in brain disorders.

Additional Information

ISBN

9780128001110

Author

Jacques Fantini - Nouara Yahi

Publisher

Elsevier|Health Sciences

Weight

0.95 Kg

Edition

1

Pages

398

Year

2015

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Brain Lipids in Synaptic Function and Neurological Disease : Clues to Innovative Therapeutic Strategies for Brain Disorders

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